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If so, nicotine is the likely culprit

Bckerman P, Hyytinen A, Kaprio J

Despite this, they are often unable to control their craving for cigarettes because the psychological dependence on tobacco is unfortunately much more powerful than their willpower

Our work advances what is currently known about the impacts of e-cigarette use on respiratory health and provides a better understanding of harm and harm reduction associated with e-cigarette use relative to cigarette smoking. Senior author and Perelman School of Medicine Department of Radiology faculty member Jacob Dubroff, MD, PhD, sees a growing role for using molecular imaging to understand the effects of electronic cigarettes

Most e-cigarettes contain nicotine, and nicotine exposure during adolescence can harm the developing brain according to a US Surgeon General Report from 2016.[13] There is incontrovertible evidence of the harmful effects of tobacco on the body