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A Cochrane systematic review, the gold standard of evidence-based medicine, explicitly concluded that it was "not able to provide reliable evidence that nicotine is a useful treatment for Alzheimer's disease [12] ." The few small studies showing modest short-term effects on some cognitive tests have not been reproduced at scale

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Following his death, Barkers girlfriend of 40 years praised his work on behalf of animal rights

The statement added, "The company regularly shares updates on our sustainability objectives and achievements at PMI.com/sustainability