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It also directly binds to KDM6A, leading to the demethylation of H3K27me3, the upregulation of Bcl-2, the suppression of Foxp3 expression, and ultimately the promotion of iTreg apoptosis [83]

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In modern life, staying up late, prolonged stress, environmental pollution, an unbalanced diet, or frequent exposure to UV rays can all increase oxidative stress

Protective effect of silymarin on oxidative stress in rat brain

the core genome ranges between more than 1000 to only 244 genes (Salama et al