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So although a person who starts to smoke in the teen years may not show any evidence of the disease until much later in life, the teen still has a high risk of accumulating mutations in his/her cellular DNA with each cigarette puff or use of a tobacco product

[88] Ibid

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According to Giovino, the per-capita consumption of tobacco products in the early 1880s was approximately 6 pounds of tobacco per person aged 18 and older

Several studies have been conducted to determine if weight loss programs should be done simultaneously during smoking cessation therapy