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To examine neuroinflammation in vivo, radioligands such as 18 F-labeled fluoroethoxybenzyl- N -(4-phenoxypyridin-3-yl) acetamide ([ 18 F]FEPPA) have been developed that reliably label the translocator protein 18 kDa (TSPO) [8, 9] for positron emission tomography (PET) scanning

Normally, these receptors are activated by the neurotransmitter acetylcholine, which is produced at both nerve endings in the brain as well as nerves of the peripheral nervous system (PNS)

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