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Normally, in a healthy, non-smoking patient the bodys immune system helps in fighting the infection

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Specifically, e-cigarette aerosol has been found to be cytotoxic to airway epithelial and macrophage cell lines [2124], as well as a variety of primary human cells such as alveolar type II cells [25], macrophages [26], small airway epithelial cells [27] and fibroblasts [28]

In contrast, cMRTP aerosols applied at equivalent nicotine concentrations had little or no effect on these markers in these cultures [40, 46]