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Over time, this THC can build up and break down into detectable THC metabolites

These would simulate a long cigarette

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For example, heating propylene glycol can create formaldehyde, a known carcinogen, and acetaldehyde, a possible carcinogen, both of which are also present in cigarette smoke, Benowitz says

In the current study, we found that cigarette smoke exposure in patients with asthma changed ILC3s rather than ILC2s