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Mental (psychiatric) problems Adderall may cause new or worse behavior and thought problems, new or worse bipolar illness, or new psychotic symptoms (such as hearing voices, or seeing or believing things that are not real) or new manic symptoms

They reviewed 14 trials of more than 8200 participants, finding 52 (1.06%) of those taking varenicline had serious adverse cardiovascular events compared with 27 (0.82%) of those on a placebo

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