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In the univariable analysis, C5-OH less than 0.22 mol/L was negatively associated with CVD in T2DM, utilizing 0.220.30 mol/L as the reference [OR (95%CI) of C5-OH for 3.0.Co;2-s 18 HouQGuanYYuWLiuXWuLXiaoMet al

It is likely that injection and chronic skin retention of this compound induced the conversion and proliferation of naive antigen-specific T-cells to a cytotoxic tissue-resident phenotype rather than recirculation of pre-existing memory cells to the skin