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This stratification strategy was employed in a companion study investigating oral health effects of ENDS

"The Last Analysis (Broadway, 1964)"

Participants in studies on nicotine pharmacokinetics have generally reported a comparable reduction in the urge to smoke between nicotine pouch use and smoking cigarettes, indicating that nicotine pouches may be an acceptable substitute to cigarettes for adult smokers

Because they're smokeless and odour-free, Zyn pouches are less regulated than traditional nicotine products