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Stepping down works best when its gradual and unforced

Treatment combines behavioral counseling (e.g., CBT) with medications such as nicotine replacement therapies (patch, gum, lozenge, spray, inhaler) and non-nicotine options like bupropion and varenicline

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Nevertheless, a significant number of biomarker-based studies, cell/ in vitro and animal studies did indicate that e-cigarette exposure can result in oxidative stress, cellular apoptosis, DNA damage, genotoxicity, and tumor growth (Figure 2, and Supplementary file Materials 2 and 3), all of which can potentially increase risk of developing lung cancer or progression of any cancer

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