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However, in one of the studies included in this meta-analysis a double-blind, controlled study in 56 adults diagnosed with MDD curcumin treatment (~880 mg/day of curcuminoids) for eight weeks was no more effective than placebo in reducing self-reported depression- and anxiety-related symptoms (101)

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J Allergy Clin Immunol 102(6 Pt 1):10331036 Pyle RC, Butterfield JH, Volcheck GW, Podjasek JC, Rank MA, Li JT, Harish A, Poe KL, Park MA (2014) Successful outpatient graded administration of trimethoprim-sulfamethoxazole in patients without HIV and with a history of sulfonamide adverse drug reaction