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Ideally all our risk estimates would have been calculated from systematic reviews and meta-analyses of alcohol consumption in non-smoking men and women, and cigarette consumption in teetotal men and women

If history and economics hold true, the substantial price increases should translate into reduced tobacco consumption, particularly among vulnerable populations, ultimately saving lives and reducing the healthcare burden associated with tobacco-related diseases

We expect that, at least in the short term, there will be little or no demonstrated effect on QALY