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At low concentrations, it is a weak inducer of CYP3A4, but at therapeutic levels shows inhibitory properties, suggesting the potential for both auto-induction and inhibition depending on the concentration (Shimokawa et al., 2015)

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The current findings are consistent with the established role of the ventral striatum and frontal cortex in drug craving, and further suggest that activity in these areas is actually reduced during active drug consumption, with the rewarding aspect of consumption mediated by more dorsal striatal regions

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Original Price $135,000 03 May 2026 $99,000 Current Price $89,900 Total price amount is based on price change information provided by the broker