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Female smokers were predicted to be twice as old as their chronological age compared to nonsmokers, whereas male smokers were predicted to be one and a half times as old as their chronological age compared to nonsmokers. According to the studys results, smokers demonstrated a higher aging ratio, and both male and female smokers were predicted to be twice as old as their chronological age as compared to nonsmokers

In 2005, the California Environmental Protection Agency released a report based on a systematic review of the literature regarding the effects of secondhand smoke, Proposed Identification of Environmental Tobbaco Smoke as a Toxic Air Contaminant. The report found that there was an increased risk of breast cancer with secondhand smoke in younger, primarily pre-menopausal women

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