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Here's American's response: "American Airlines does not allow electronic cigarettes to be used onboard." Delta's answer was similar: "Delta does not permit the use of electronic cigarettes on board any Delta or Delta Connection aircraft." In an April 2010 issue of its "Spirit" magazine, Southwest Airlines classified "electronic cigarettes and smoking devices" as "Never Permitted" (via the Global Advisors Smokefree Policy)

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Even as smoking trends have evolved, tobacco-related disease remains the number one cause of preventable death