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Considering the described counteraction of the systemic corticosteroid-impaired healing (i.e., tendon injuries [94,95,96,97] and burns [143,144,145]), BPC 157, given either intraperitoneally or locally, completely eliminated the damage induced by systemic corticosteroid application in rats with crushed gastrocnemius complex [46]
Loeser, R
This is true in both short-term trials and in studies lasting up to 18 months and for doses as high as 8,000 to 12,000 milligrams or 8 to 12 grams
Int Clin Psychopharmacol 16:8792 Bilici M, Ozturk C, Dursun H, Albayrak F, Saglam MB, Uyanik A, Gulaboglu M, Tekin SB (2009) Protective effect of mirtazapine on indomethacin-induced ulcer in rats and its relationship with oxidant and antioxidant parameters