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But their use has become controversial due to a lack of evidence on their efficacy as anti-smoking aids, warnings about possible long-term health effects and numerous studies showing that teen use is a direct gateway to traditional cigarette smoking

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A participant received the same warning for the duration of the study

Frank P, Morris J, Hazell M, Linehan M, Frank T (2006) Smoking, respiratory symptoms and likely asthma in young people: evidence from postal questionnaire surveys in the Wythenshawe Community Asthma Project (WYCAP)