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The patients were evaluated for six months after discharge from a voluntary inpatient treatment program at the Psychiatry Institute of Hospital das Clnicas (HC), the general hospital run by the University of So Paulo Medical School (FMUSP)

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The average measured toxicant result for each VELO nicotine pouch sample was compared with the average measured toxicant result for the reference cigarette emissions (at ISO Intense smoking regime, ISO 20778:2018 2 )

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