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Lung cancer is also causally associated with cigarette smoking, accounting for around 90% of lung cancer cases (Addissouky and Khalil 2020)

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a way to reduce their capacity to burn when not being actively smoked

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In the epidermis of smokers, we observed a significant upregulation of filaggrin, loricrin, and a trend of increased involucrin but no differences were found in the case of transglutaminase 1 and kallikrein-related peptidase 7, on the gene and protein levels