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Because it bypasses IGF binding proteins, its local effects are intense , and excessive use can lead to systemic spillover

Am J Clin Nutr 76:703716

The study also found that in MCPI, elevated GPOX and reduced APX activity contributed to H 2 O 2 buildup, crucial for defense establishment

Its critical for detoxifying harmful substances in the liver, recycling other antioxidants like vitamins C and E, and maintaining a robust immune response