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Furthermore, and consistent with the reductions in toxicological impact, these exposure reductions were associated with beneficial changes in biomarkers of potential harm among switching smokers [58, 60, 65, 69,70,71,72], which themselves are indicators of future disease risk
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However, Faasen emphasized that the region does lack some of the flavors for FCV and burley that can be produced in the US, Brazil, and parts of Africa, as well as the top-quality, full-flavored Oriental tobaccos produced in the classical growing areas of Europe
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