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Specialised Materials Using specialist alloy steels specifically developed over many years in collaboration with our major global industry partners and our expert metallurgists, Arkote cigarette rod cutting knives are specifically manufactured to meet the demands of modern day cigarette makers

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The nicotine patch will be dispensed weekly during this titration phase, with dose adjustments made by the study physician at each weekly study visit based on tolerability and the average number of cigarettes smoked per day (CPD) in the preceding week (see Table 1 for the dosing algorithm based on amount of continued smoking)

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