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"On the individual level it is, I would put forward, it's a very, very, very low amount of nicotine." Vose said propylene glycol is used as a carrier for nicotine in e-liquids and that the FDA has recognized the substance as generally safe for oral and dermal use

Smoking cessation duration was defined as the interval between a quit attempt (from 1 day to several years) and relapse, where relapse essentially means commencing smoking after abstinence for a period 20-23

But its popularity slipped in the 2000s when it became a Schedule III drug and concerns were raised over side effects including hallucinations and, in rare cases, seizures

Flavor was the third most commonly reported reason

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