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Data from participants who received the same injection dose (the saline injection group and the 1 10 7 DPSCs per tooth injection group) across both trials were pooled for analysis, and baseline characteristics for these combined participants were verified (Supplementary Table 13)

As such, this review highlights the urgent need for clinical trials targeting antiangiogenic therapies in neurodegenerative diseases, because without robust data from clinical studies, the efficacy and safety of such interventions remain speculative

Conditions such as kidney failure, chronic kidney disease, and nephrotic syndrome have been associated with fluid retention in the face and lower limbs

For patients with pernicious anemia, severe malabsorption, or acute neurological symptoms, injections remain the appropriate clinical choice