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How smoking leads us to cancer is by damaging our DNA, including some key genes that give us protection against the cancer

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As Madison agreed in Federalist 56 , It is a sound and important principle, that the representative ought to be acquainted with the interests and circumstances of his constituents. With the large population of the United States, representation in the House is now based on districts that each have, on average, about three-fourths of a million residents, roughly the size of the largest state in the Union in 1790, Virginia