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This mutational fingerprint is considered a smoking signature, which has been ascribed to tobacco smoke constituents, such as PAHs and specific ROS [31, 51, 172174]
As a teenager in East Tennessee, she could hardly wait until she was old enough to leave home and move to Nashville, TN
The original smoking consumption questions (and questions from 2022 onwards) asked participants: "How many cigarettes a day do you usually smoke on weekdays?" "How many cigarettes a day do you usually smoke on weekends?" The altered smoking consumption question for 2018 to 2019 asked participants: "How many cigarettes a day do you usually smoke Monday to Sunday?" The respondent is requested to enter a number for each day, or select: don't know for each day prefer not to answer Given the changes and interruptions in the delivery of this question, current smoking consumption estimates cannot be reliably compared from year to year between 2018 and 2021
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