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Based on current knowledge stating that vaping is at least 95% less harmful than smoking remains a good way to communicate the large difference in relative risk so that more smokers are encouraged to make the switch from smoking to vaping. With heated tobacco products (HTP), the situation is slightly different because tobacco is involved and is heated (at different temperatures depending on the device) although never above 350C, and so below the combustion temperature of cigarettes

21 This increase in the false-positive assessment of the degree of toxicity could lead unnecessary escalation of care

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doi: 10.1164/rccm.202310-1871LE

A large number of people try to give up smoking, but not all succeed