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First, there are challenges to bioavailability, which would involve rapid systemic elimination or possible solubility issues, as highlighted in preclinical pharmacokinetic studies ( Safety assessments of caudatin derivatives have offered assurance, but limited data are available on their long-term toxicity

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Bone loss during the fat loss period (fat loss model in obese rats) Experimental Design: Animals: Obese SD rats induced by high-fat diet were randomly divided into an obesity control group, a simple weight loss group (30% calorie restriction), and a weight loss+AOD 9604 group (500 g/kg/day)

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V., Waring, A

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Computational studies suggest that certain tripeptides may function as vehicles for drug delivery systems

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