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Allergic reactions can manifest as skin rashes, hives, or difficulty breathing

Medicated chewing gum containing 2mg nicotine has been used for many years for smoking cessation, where E-Cigarettes and vaping have been a more recent addition to the variety of smoking cessation tools

Control patients with any previous history of cardiovascular or cerebrovascular diseases were excluded, resulting in a total sample of 344 participants (172 cases and 172 controls), with a power of 80% and a 95% confidence level

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The percentage of immunoreactive area was calculated as follows: the percentage of each immunoreactive area in the brain subregion per section = [each immunoreactive area in the brain subregion of each section]/[total area of the brain subregion of each section: neocortex and hippocampus]