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A study in isolated mouse mitochondria showed that the mitochondrial ability to buffer calcium was reduced by 20% following treatment with the nAChR agonists choline, acetylcholine and PNU282987 (Gergalova et al

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'California and Massachusetts were early adopters of such policies and others have more recently done so like New York and New Jersey, resulting in lower smoking rates.' He added that states have also benefitted from an influx of immigrant groups such as Hispanics with a traditionally low prevalence of smoking

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