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Most flavorings in e-liquids are designated as generally recognized as safe (also known as GRAS) by FDA, but those designations are for oral consumption in food and do not apply to flavorings used in e-cigarettes

An electronic cigarette (colloquially known as a vape or e-cig) is a handheld, battery-powered device designed to recreate the feeling of smoking

JAMA Intern Med 2019 Sep 16

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