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All these mechanisms lead to MS-like motor symptoms observed in patients with Cbl deficiency such as subacute degeneration of the spinal cord [84]

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This seems to be the case for short-term exposure to antimicrobials, but studies of long-term antibiotic use have reported that perturbations in gut microbiota and resistome can have either long-lasting irreversible effects or can persist for longer periods 16,18,25

Nevertheless, minimizing light exposure extends shelf life

All bedding and enrichment materials were sterilized by autoclaving before use