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The peptide's activation of ERK1/2 and downstream transcription factors including Egr-1 drives expression of collagen synthesis genes while its enhancement of cellular migration ensures efficient fibroblast recruitment to sites requiring matrix deposition, creating optimal conditions for rapid yet organized tissue reconstruction

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The extended half-life of 20-30 hours has been confirmed in multiple studies, and research has shown that steady-state levels can be achieved with daily use

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