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P.KumarA.DwivediS.DeebaF.KumarS.et al (2015a)

These include alterations in the monoaminergic system, changes in glutamatergic synaptic transmission, neuro-inflammation, alterations in the hypothalamic-pituitary-adrenocortical (HPA) axis, changes in brain-derived neurotrophic factor (BDNF), and hippocampal atrophy ( However, depression in AD is more specifically linked to deficits in certain brain regions and AD-related pathological changes

Glutathione inhibits tyrosine activity which reduces the prodcution of eumelanin and promotes the pheomelanin production

Data compiled by SHOOK Research LLC based on the time period from 3/31/22 - 3/31/23

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