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Research shows that tobacco use can lower sperm quality, damage sperm DNA and even contribute to infertility

The competitive binding of nicotine to nicotinic cholinergic receptors induces a rapid transient allosteric conformational change to form a selective ionic channel

Text and graphic warnings on cigarette packages: findings from the international tobacco control four country study

Public opinion has all along been fully prepared to treat the matter as a joke but for the uncomfortable reflection that the antisaloon campaign, which was for so long ridiculed led to a successful conclusion on the legal, if not on the practical side