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In the future, we will develop small molecule inhibitors or activators for specific transporters such as SLC25A39 and xCT, and use gene editing tools (such as CRISPR/Cas9) to precisely edit related genes to achieve precise regulation of GSH metabolism, providing more targeted means for disease treatment
The cell index was defined as R n -R b at each time point of measurement, where R n is the cell-electrode impedance of the well when it contains cells, and R b is the background impedance of the well with the medium alone
De Bont, L., Donnay, N., Couturier, J., & Rouhier, N