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according to Osteoarthritis Research Society International (OARSI) guidelines, non-steroidal anti-inflammatory drugs (NSAIDs) can only provide short-term symptom relief while carrying substantial risks of adverse gastrointestinal and cardiovascular events (Bannuru et al., 2019)

[DOI] [PubMed] [Google Scholar] Iles KE, Liu RM

Additional experiments demonstrated that mice maintained on a Se-deficient diet had significant increases in LPS-mediated infiltration of lung macrophages when compared with animals maintained on a Se-adequate diet ( Reference Vunta, Belda and Arner 45 )

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While some individuals may not experience any adverse effects, others might encounter varying symptoms