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In This Article: In a study of over 2,000 promotional Instagram posts for 25 synthetic nicotine brands, only 263 posts (13%) adhered to FDA health warning requirements Posts that included health warnings and a larger warning size received less user engagement Enforcement of FDA-compliant health warnings on social media may reduce youth engagement with synthetic nicotine and tobacco marketing In a new study published in the Journal of the American Medical Association (JAMA) Open Network , researchers including lead author Jiaxi Wu, now a postdoctoral fellow at the Health Communication & Equity Lab at the Annenberg School for Communication, analyzed over 2,000 Instagram posts by synthetic nicotine e-cigarette brands and found that 87% did not adhere to Food and Drug Administration (FDA) guidelines for tobacco marketing