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Although IV is frequently associated with atopic dermatitis, only half of the patients with this inflammatory disease associate pathogenic variants in FLG.13 IV is caused by semi-dominant pathogenic variants in FLG14a gene encoding the filaggrin proteinthe major protein inside corneocytes

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Menthol being a popular flavor among the youth and adults 12 and a series of vanilla flavors as well as rainbow candy which were earlier evaluated for free radical generation 13