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So, why the huge difference between smokers and non-smokers

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In 2014, the Surgeon Generals Report on the Health Consequences of Smoking stated that the evidence is sufficient to conclude that the increased risk of adenocarcinoma of the lung in smokers results from changes in the design and composition of cigarettes since the 1950s. The one thing really new about the current study is the authors recommendation that the Food and Drug Administration undertake an active study to determine whether the use of filters in cigarettes should be prohibited, Edelman said