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Increased NO bioavailability locally in the respiratory tract could be mediated transiently via inhaled tobacco smoke [52] and/or through tobacco smoke modulation of endogenous NO generation through eNOS induction (vide infra, Fig
[10] Compassionate Investigational New Drug program After Robert Randall became the first person to successfully use a medical necessity defense when he was charged with illegal possession of cannabis to treat his glaucoma, he filed a federal lawsuit, Randall v
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