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"Addiction is primarily defined as a loss of control on the use of a substance and continued use despite the consequences," Bernard Le Foll, Chair of Addiction Psychiatry within the Department of Psychiatry at the University of Toronto, told Live Science in an email

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Smoking-related factors can interfere with the production and activity of growth factors, such as transforming growth factor beta (TGF-), which play a critical role in tissue repair 135

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