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The diagnosis of EDS is based primarily on clinical history, family history to clarify inheritance and careful physical examination to evaluate involvement of the various systems

Plasma C-reactive protein, sodium, potassium, glucose, cystatin-C, creatinine, triglyceride, and total, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol concentrations were determined using Cobas Integra 700/800 (F