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Collider bias can arise if there are confounders of the effect of smoking on vaping (denoted intermediate confounders in the diagram), such as individual smoking histories, or parental smoking/vaping (for youth)

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Indeed, nicotine acts on the central nervous system and increases the release of certain hormones that can reduce the desire to eat

In the UK, where vaping is more widely accepted as a quitting aid, many smokers have found success using the best vape to quit smoking uk options available

Postdiagnosis smoking cessation and reduced risk for lung cancer progression and mortality: a prospective cohort study