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During the initial visit to the dental clinic on September 29, 2021, more than a year after oral symptoms began, an intraoral examination revealed a light yellow-brown discoloration and coating on the dorsum of the tongue (Figure 1A)

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During the investigation, 7-Eleven sent additional notices regarding the law to stores within defined school zones, removed vapes and other electronic smoking devices from the shelves of those stores and removed the devices from inventory systems for those stores so they cannot be sold

Emerging therapies based on this relatively recent understanding are testing for instance probiotics to treat clinical depression (Nikolova et al., 2019)

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