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Two variants of the Neo THP consumable rod with different nicotine contents were used with an identical heating device: The THP1.0(RT) consumable rod yielded 0.46 mg nicotine/stick and THP1.1(RT) yielded 0.68 mg nicotine/stick, as measured under a modified Health Canada Intense machine smoking regime (55 mL puff volume, 30 s puff interval, 2 s puff duration, 8 puffs, no vent blocking) 22,48

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Tobacco by Vaporlax boasts an intense tobacco taste that is free from added sweetness, closely resembling a combustible in flavor

Furthermore, NNK triggered cellular injury in the pancreas (vacuolization, pyknotic nuclei, and edema) similar to that typically seen during AP