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Further evidence comes from a study in which 84% of women who reported themselves as nonsmokers with smoking partners had detectable levels of cotinine (a major metabolite of nicotine that can have a negative impact on fertilization rates) in the follicular fluid surrounding their eggs upon retrieval during IVF

European Urology Oncology

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Retrieved November 22, 2013

There is also evidence for interactions of exposure to secondhand smoke with other cardiovascular risk factors in youth