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August 15, 2006

Age, sex, and race were covariates included in the model due to their associations with tobacco use in the previous literature 8,14,16

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A separate study also found protein levels of IL-6 and IL-8 to be increased in co-cultured primary gingival epithelial cells and fibroblasts in response nicotine-containing e-cigarette exposure and MCP-1 and TNF protein concentrations to be elevated independent of nicotine content (90)

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