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Comorbidities like type 2 diabetes and metabolic syndrome a cluster of metabolic disorders that includes obesity, dyslipidemia, hypertension, and insulin resistance, leading to chronic systemic inflammation

That said, there is still limited human evidence comparing oral and injectable forms for tendon healing

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In addition to glomerular filtration, there is net tubular secretion of oxalate [51, 52, 53], mainly in the proximal tubule, although there is also evidence for oxalate transport in collecting duct and papillary cells [54, 55]